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How Long Does it Take for CBD Oil to Work?

The use of CBD oil has increased as people are continuously finding a range of benefits when it is ingested. However, despite the surge in popularity, the process of CBD interacting in the body isn’t quite as well known and has led to much questioning. Many people who use CBD aren’t sure how long it will take to work and how long the effects will last. 

Scientists are still researching the incredible impact that CBD can have on your body. Understanding the rate of how CBD works in the body really depends on how you consume your CBD oil and the product you are using. 

These factors contribute to how the body responds to CBD and how rapidly it takes effect. Understanding these two factors can help you take CBD efficiently to ensure your consumption is beneficial and you feel the effects much quicker. 

How CBD Interacts with Your Body

There are several mechanisms that allow for CBD to interact with the brain and the body. When ingested, CBD interacts with the body through the endocannabinoid system, otherwise known as the ECS. 

It uses the CB1 and CB2 cannabinoid receptors to interact with a wide range of proteins in the body as well as communicating with the central nervous system through the receptors. How CBD interacts with the body is incredibly important and is what ensures particular health benefits. 

When it is introduced to the endocannabinoid system, it obstructs the absorption of anandamide which is a natural cannabinoid molecule. Anandamide is what regulates pain and using CBD can ensure that those who are chronic pain sufferers get relief from their symptoms.

Another thing about CBD’s interaction with the body is how it reacts with other receptor proteins that aren’t directly involved with the ECS. This includes the vanilloid receptor, TRPV1, and the serotonin receptor, 5-HT1A. Scientists believe that the pain-relieving and anti-inflammatory properties that appear to be present in CBD could stem from the activation of these biological receptor pathways. 

While it is a complex process, the method of consumption, individual body chemistry, and even the quality of the CBD can determine how it moves through your body and how long it can take to leave your system. One thing is certain though: it can interact positively and create natural remedies for ailments. 


How to Consume CBD for Maximum Effect

As previously mentioned, how CBD is consumed can determine how long it will take to feel the effects of CBD in the body. While it is available in a myriad of different forms, each has a differing effect on the body and how long it takes to interact with your receptors. 


Arguably the most common method of CBD oil consumption, ingesting CBD oil usually involves a user ingesting a couple of drops directly through the mouth. One thing to note here is that if you swallow the oil immediately, you can significantly decrease the amount of CBD that enters your bloodstream as some of then is getting directly broken down in the digestive track before being sent to the liver. 

While CBD compounds can be metabolised by the liver, research has shown that it goes through something known as the ‘first pass effect’. This is where enzymes in the liver actually reduce CBD concentration before it is sent into the bloodstream to be circulated through the body to feel the beneficial effects of CBD.

This issue also occurs when ingesting CBD edibles. Using CBD gummies or products of that calibre will go through the same process as ingesting it through your mouth which dilutes the amount of CBD going into the bloodstream due to it going through the digestive tract first. This can also increase the amount of time it takes for you to feel the effects of the compound as it only reaches the bloodstream at a later stage.   

The majority of the 'first pass effect' can be avoided by simply putting your CBD tincture not on top of the tongue, but under in a process called sublingual absorption. 



CBD oil can be consumed sublingually by placing drops of CBD under your tongue to allow the capillaries in the tissue to absorb it. You can rub it into the tissue with your tongue or finger or allow it to be absorbed. It is recommended that you hold it under the tongue for at least 30 seconds to a minute before you swallow. 

By doing this, you allow mucous membranes in your mouth to absorb the CBD, helping for some to enter the bloodstream without the long process of it going through the digestive tract before being metabolised by the liver. This ensures that it goes into the bloodstream quicker and and at a higher rate meaning effects can be felt within minutes rather than hours. 

Not only do you receive the benefit a lot faster, less of the compound will also be broken down by the liver and in the digestive track as the majority of it will already have absorbed within the oral cavity, under the tongue. 

Effects from ingestion through sublingual administration will be felt within thirty minutes. You should feel the effects for over an hour but they will be propped up again through the digestive tract absorption around two hours in. 



When people think of inhaling CBD, there is often some confusion with the inhalation of marijuana that is rich in THC. CBD can be inhaled and there are plenty of products that allow you to CBD and reap its benefits through this method.

CBD inhalation is considered an effective way to take CBD as it is rapidly absorbed into the body and can be done easily through vaping. This is due to the fact that, when you vape CBD oil, the cannabinoids are directed to your lungs where they can rapidly enter the bloodstream. This means that it can circulate throughout the body almost instantly, and it is one of the fastest CBD administration methods. 

Peak concentrations of CBD can be felt within three minutes of taking your first couple of draws. This method is perfect for people who are looking for instant relief, such people prone to pangs of anxiety or pain that have to be tackled quickly.



One easy and effective way to absorb CBD is through transdermal patches. Similarly to nicotine and birth control patches, the beauty of using CBD patches is that they deliver a long-lasting dose for users very efficiently. This works by the cannabinoid diffusing into skin through skin cells which takes it directly into the bloodstream. This is helped through permeation enhancers making absorption more efficient. 

Transdermal absorption is incredibly useful for people who suffer from localised skin or chronic muscle issues. They allow for a good amount of CBD to be taken into the bloodstream in a short amount of time in a discreet manner - a perfect way to take CBD during the day without impeding your activities. 

A great way of administering CBD, the CBD patch allows for the cannabinoid effects to last for several hours, depending on the patch formulation, and they work within an hour of being placed on skin. 


Another way of absorbing CBD is using topical CBD products. These work by placing it on the skin where the CBD is absorbed and slowly interacts with localised cannabinoid receptors within the body. 

An issue with this type of application is that there is a lower rate of cannabinoid absorption using topicals. Thus, applying topicals liberally to the skin should ensure that there is a speedier absorption rate.

Mostly used for those who suffer from chronic pain, topical CBD can be applied directly to problem areas. You will feel the effects around 90 minutes after you have applied.

How to Dose with CBD for Maximum Effect

The second major factor when considering the length of time it takes for CBD oil to work in the body is dosage. Dosage varies person to person, so when taking into account CBD dosage, an individual’s circumstances are critical for correct CBD concentration.


Weight is an important factor when determining CBD dosage as the body influences the amount of CBD that is needed before effects are felt. The larger your body mass, the larger amount of CBD is required to remain in your bloodstream. 

This also contributes to how the potential effects will be felt. Something to note is that CBD is stored in fat cells which are eventually removed from the body through urine and excretion. 


Another factor that contributes to how long CBD remains in your system is your metabolic rate. This determines the length of time needed for the body to break down and synthesise compounds within it. This means that this will directly affect how long it takes for the body to process and metabolise CBD as a cannabinoid. 

Frequency of Use 

How often you take a product and the quality of that product will also determine how well CBD works in your body. Finding the optimal dosing regimen will depend on the type of product, the amount of CBD inside of it, and what you are taking CBD for. 

Companies and reputable manufacturers always provide instructions on how to use the product and will give you guidance on dosage. However, you will find that you might have to amend these to find your optimal dose that is designed to fit your requirements.

The CBD Dosage You Should Take

Knowing the ideal dosage is an important part of the CBD treatment process as it lets you know what your body needs to ensure the desired effects of CBD within your system and the length of time it resides there. 

Due to the fact that CBD isn’t a psychoactive substance, there is no worrying about dosage amount as you will not get an intoxicated feeling. It is recommended that you start with a lower dosage and gradually increase this until you receive the ideal effects.

Most companies recommend that you use a millilitre of CBD oil or tincture when starting out or 10 milligrams of an edible like a CBD gummy. From here, you will be able to observe how you respond to this dosage before having more. 

How Long Does CBD Take to Leave Your System?

While it is important to consider how long it takes before CBD interacts with receptors to produce desired effects, it is also important to consider how long it lasts in your bloodstream. Every factor that we have covered prior to this should be taken into consideration. 

For example, if you have vaped CBD, it will be present in your bloodstream for up to 72 hours after it was inhaled. From a 2018 review, it was discovered that CBD has an estimated half-life of two to five days from oral dosing. This varies through delivery method though. 

How CBD affects Drug Tests

A lot of people are worried about using CBD due to it's association with THC, the main compound found in marijuana which drug tests are made to recognise. Due to its chemical structure, it is highly unlikely that CBD would show up on a drug screening as they are designed to find THC. 

While full spectrum CBD oils can contain trace amounts of THC, you would have to consume CBD oil in the estimated region of 1,000 to 2,000 milligrams per day to be able to get a false positive test result. 

A way to avoid worrying about this happening is using products that contain pure CBD isolate or broad-spectrum oil. The former contains no THC or other plant based cannabinoids which will ensure that you do not have any issues when taking a drug test. The latter contains trace amounts of THC that might have been present in the hemp plant, but not enough to cause any worry. 

CBD and Your Body 

To recap, CBD that is consumed orally through ingestion will take up to two hours to feel any effects. Using sublingual administration will see effects from 30 minutes in the body. CBD oil can be used effectively to treat anxiety conditions and it is advised to vape CBD or administer it sublingually to see the quickest effects. 

CBD’s effectiveness depends on the quality of the CBD oil, the consumption method, and what your requirements are. CBD is non-intoxicating so you can experiment with dosage until you find optimal circumstances for your needs with very little risk. It is advisable to speak with your doctor before trying CBD products though.

For pain relief, it is advisable to use topical products for localised pain. This can take between minutes and hours, depending on the strength of the topical. Ensure that the products you use are licensed and from reputable companies like CBD Farmacy. 

Using CBD for You

CBD has a host of well known benefits that provide plenty of relief for ailments such as chronic pain and anxiety. How CBD works for you depends on a variety of factors like the way it is consumed, the weight of the person, and its dosage.

If you would like to learn more about CBD and require information around products, get in touch with CBD Farmacy. We offer a variety of products from oils and tinctures to topicals and pastes. Find out what suits you best today. 


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